Kathleen M. Darcy

First-year surgical intern Meredith Grey begins her first day in the demanding residency program at Seattle Grace Hospital.

The interns compete to treat severe injuries as patients from the annual bike-messenger race fill the emergency room. Christina and Izzie face a difficult situation with a brain dead patient.

Leslie tries to stop a high school punk who vandalises the park every Halloween, but will he get the last laugh? Meanwhile, Ann's Halloween party is a bore until Tom saves the day.

Meredith's fears of a bad day are realised when a medical case threatens the lives of everyone in the OR; Izzie decides to take things further with Alex.

Derek and Addison's disagreements become professional when their close friends have a medical crisis; Cristina and Burke try to have a normal date but it does not got as planned.

Cristina is revealed to be a difficult patient as she recovers; Meredith's mother has the staff running in circles.