Richard Jenik

Claire and Phil embarrass Haley when they drop her off at college. Then, Manny makes Gloria and Jay take a class, and Lily gets into a tussle on her first day of kindergarten.

Cristina and Preston have philosophical differences over a young boy who needs a heart transplant; the interns help Alex prepare for his exam re-sit; Meredith reminds Izzie about the true meaning of Christmas.

Susan calls off a wedding; Gaby moves forward with a wedding; a Wisteria Lane resident is suspected of murder.

A photograph of Tim (Tim Allen) and his new female mechanic (guest star Jenny McCarthy) puts a damper on Jill (Patricia Richardson) and Tim's wedding anniversary.

The team investigates if 15-year-old whiz kid Ryan Wallace is missing of his own accord in order to execute his elaborate plan to bomb his high school. The agents learn that the missing student is an unpopular worrier who has obsessed about safety issues since his father's fatal mugging. They initially surmise that Ryan's disappearance may have something to do with the school bullies who picked a fight with him.